Product Description

Avangio (Bevacizumab) is a recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF).

Avangio contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Avangio is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium and has a molecular weight of approximately 149kDa.

Indications

• Metastatic Colorectal Cancer (mCRC)
• Non-squamous Non-small Cell Lung Cancer (NSCLC)
• Glioblastoma (GBM)
• Metastatic Renal Cell Carcinoma (mRCC)
• Persistent, Recurrent, or Metastatic Carcinoma of the Cervix
• Metastatic Breast Cancer (mBC)

Storage

• Store at 2°C to 8°C
• Protect from light
• Do not freeze or shake

Shelf-life

24 months from the date of manufacture